Treats poisoning due to those pesticides and chemicals. Sold as Protopam Chloride, Pralidoxime Chloride. Every FDA application for this active ingredient: 4 branded and 1 generic.
As of Nov 15, 2026, FDA lists 5 applications for Pralidoxime Chloride (sold as Protopam Chloride, Pralidoxime Chloride), first approved Mar 11, 1964, with 0 new uses approved and 0 published complete response letters.
| Study | Phase | Status | Posted |
|---|---|---|---|
| Magnesium Sulphate With Atropine and Pralidoxime vs Standard Therapy Alone in Acute Organophosphate PoisoningOrganophosphate Poisoning · Muhammad Aamir Latif | Not applicable | Recruiting | Aug 20, 2026 |
| Mar 11, 1964 | Protopam ChlorideNDA 14134 · New molecular entity | Baxter Hlthcare Corp | 23 | Marketed |
| Mar 12, 1964 | Protopam ChlorideNDA 14122 · New dosage form | Wyeth Ayerst | 10 | Discontinued |
| Dec 13, 1982 | Protopam ChlorideNDA 18799 · New dosage form | Baxter Hlthcare Corp | 1 | Discontinued |
| Apr 26, 1983 | Pralidoxime ChlorideNDA 18986 · New formulation or manufacturer | Meridian Medcl Techn | 24 | Discontinued |
| — | Pralidoxime ChlorideANDA 72224 | Quad Pharms | 0 | Discontinued |
Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient. Drugs@FDA
Baxter Hlthcare Corp