Drug Price Changes
Every week CMS surveys what pharmacies pay wholesalers for prescription drugs, per tablet or millilitre. Comparing this week with the same week last year shows which generics got more expensive and which drugs got cheaper, usually because a generic arrived.
What US retail pharmacies paid per unit for 4,758 prescription drug products in the week of Nov 11, 2026, from CMS's National Average Drug Acquisition Cost (NADAC) survey, against the same week a year earlier.
- Median change in a year: -0.3%
- Up by half or more: 38
- Down by half or more: 79
- Generic products: 66%
- Survey week: Nov 11, 2026
Biggest Increases
Percent change in price per unit since Nov 12, 2025, one strength per drug.
- BACTERIOSTATIC WATER VIAL$0.0822 → $0.219+167%
- K-PHOS NEUTRAL TABLET$0.201 → $0.502+150%
- PHOSPHA 250 NEUTRAL TABLET$0.201 → $0.502+150%
- UREA 40% CREAM$0.279 → $0.668+140%
- VERAPAMIL ER 120 MG CAPSULE$1.22 → $2.92+139%
- WATER FOR INJECTION VIAL$0.133 → $0.310+133%
- CAPTOPRIL 100 MG TABLET$0.284 → $0.634+123%
- KLOR-CON M20 TABLET$0.0670 → $0.142+112%
- LORAZEPAM 2 MG/ML VIAL$1.09 → $2.12+95%
- DOXEPIN 10 MG/ML ORAL CONC$0.462 → $0.888+92%
Biggest Drops
Usually the first generics arriving; one strength per drug.
- DAPAGLIFLOZIN 5 MG TABLET$11.5 → $0.163−99%
- TICAGRELOR 60 MG TABLET$5.94 → $0.262−96%
- DAPAGLIFLOZIN-METFORMIN ER 10-1,000 MG TABLET$11.7 → $0.815−93%
- SODIUM CHLORIDE 0.9% SOLUTION$0.0262 → $0.00214−92%
- DASATINIB 100 MG TABLET$192 → $24.1−87%
- TEMOZOLOMIDE 20 MG CAPSULE$4.11 → $0.880−79%
- SERTRALINE 150 MG CAPSULE$5.17 → $1.15−78%
- IVABRADINE HCL 5 MG TABLET$2.99 → $0.710−76%
- FINGOLIMOD 0.5 MG CAPSULE$5.74 → $1.42−75%
- FIASP PENFILL 100 UNIT/ML CART$34.4 → $8.54−75%
Every Product
Biggest moves first, up or down; sort by price or name, or search a drug.| DAPAGLIFLOZIN 5 MG TABLETGeneric | $0.163per tablet or unit | $11.47 | -99% |
| DAPAGLIFLOZIN 10 MG TABLETGeneric | $0.184per tablet or unit | $11.49 | -98% |
| TICAGRELOR 60 MG TABLETGeneric | $0.262per tablet or unit | $5.94 | -96% |
| DAPAGLIFLOZIN-METFORMIN ER 10-1,000 MG TABLETGeneric | $0.815per tablet or unit | $11.75 | -93% |
| SODIUM CHLORIDE 0.9% SOLUTIONGeneric | $0.002per ML | $0.026 | -92% |
| DAPAGLIFLOZIN-METFORMIN ER 5-1,000 MG TABLETGeneric | $0.487per tablet or unit | $5.87 | -92% |
| DASATINIB 100 MG TABLETGeneric | $24.09per tablet or unit | $192 | -87% |
| TEMOZOLOMIDE 20 MG CAPSULEGeneric | $0.880per tablet or unit | $4.11 | -79% |
| SERTRALINE 150 MG CAPSULEGeneric | $1.15per tablet or unit | $5.17 | -78% |
| IVABRADINE HCL 5 MG TABLETGeneric | $0.710per tablet or unit | $2.99 | -76% |
| IVABRADINE HCL 7.5 MG TABLETGeneric | $0.603per tablet or unit | $2.50 | -76% |
| FINGOLIMOD 0.5 MG CAPSULEGeneric | $1.42per tablet or unit | $5.74 | -75% |
| FIASP PENFILL 100 UNIT/ML CARTBrand | $8.54per ML | $34.38 | -75% |
| FIASP PUMPCART 100 UNIT/MLBrand | $8.57per ML | $34.43 | -75% |
| FIASP 100 UNIT/ML FLEXTOUCHBrand | $8.91per ML | $35.74 | -75% |
| FIASP 100 UNIT/ML VIALBrand | $6.92per ML | $27.74 | -75% |
| RIVAROXABAN 2.5 MG TABLETGeneric | $0.626per tablet or unit | $2.40 | -74% |
| TRESIBA FLEXTOUCH 200 UNIT/MLBrand | $18.06per ML | $65.05 | -72% |
| TRESIBA FLEXTOUCH 100 UNIT/MLBrand | $9.03per ML | $32.53 | -72% |
| TRESIBA 100 UNIT/ML VIALBrand | $9.02per ML | $32.47 | -72% |
| CETIRIZINE HCL 1 MG/ML SOLNGeneric | $0.022per ML | $0.077 | -71% |
| SERTRALINE 200 MG CAPSULEGeneric | $1.47per tablet or unit | $5.12 | -71% |
| LYUMJEV 100 UNIT/ML VIALBrand | $7.87per ML | $26.31 | -70% |
| LYUMJEV 200 UNIT/ML KWIKPENBrand | $20.28per ML | $67.76 | -70% |
| LYUMJEV 100 UNIT/ML KWIKPENBrand | $10.15per ML | $33.90 | -70% |
| HUMALOG 200 UNIT/ML KWIKPENBrand | $20.31per ML | $67.78 | -70% |
| LYUMJEV TEMPO PEN 100 UNIT/MLBrand | $10.14per ML | $33.79 | -70% |
| TERIFLUNOMIDE 14 MG TABLETGeneric | $0.223per tablet or unit | $0.738 | -70% |
| ALLOPURINOL 200 MG TABLETGeneric | $1.87per tablet or unit | $6.12 | -69% |
| ESTRADIOL 0.1% (0.75 MG) GEL PKGeneric | $0.674per tablet or unit | $2.11 | -68% |
| TOLVAPTAN 15 MG TABLETGeneric | $11.78per tablet or unit | $36.77 | -68% |
| SAXAGLIPTIN HCL 5 MG TABLETGeneric | $1.07per tablet or unit | $3.29 | -68% |
| TIMOLOL 0.25% GEL-SOLUTIONGeneric | $6.29per ML | $18.65 | -66% |
| ESLICARBAZEPINE 600 MG TABLETGeneric | $1.62per tablet or unit | $4.73 | -66% |
| METHOTREXATE 250 MG/10 ML VIALGeneric | $0.702per ML | $1.96 | -64% |
| FORMOTEROL 20 MCG/2 ML NEB VLGeneric | $1.24per ML | $3.41 | -64% |
| ISOTRETINOIN 10 MG CAPSULEGeneric | $4.21per tablet or unit | $11.38 | -63% |
| BACTERIOSTATIC WATER VIALGeneric | $0.219per ML | $0.082 | +167% |
| DIMETHYL FUMARATE DR 120 MG CPGeneric | $0.382per tablet or unit | $1.02 | -62% |
| EVEROLIMUS 1 MG TABLETGeneric | $5.49per tablet or unit | $14.39 | -62% |
| SILDENAFIL 10 MG/ML ORAL SUSPGeneric | $0.234per ML | $0.610 | -62% |
| ESLICARBAZEPINE 800 MG TABLETGeneric | $1.52per tablet or unit | $3.95 | -61% |
| ISOTRETINOIN 40 MG CAPSULEGeneric | $5.83per tablet or unit | $15.05 | -61% |
| GABAPENTIN ER 300 MG TABLETGeneric | $0.623per tablet or unit | $1.60 | -61% |
| VENLAFAXINE HCL ER 75 MG TABGeneric | $0.290per tablet or unit | $0.736 | -61% |
| K-PHOS NEUTRAL TABLETGeneric | $0.502per tablet or unit | $0.201 | +150% |
| PHOSPHA 250 NEUTRAL TABLETGeneric | $0.502per tablet or unit | $0.201 | +150% |
| TETRACYCLINE 250 MG CAPSULEGeneric | $0.267per tablet or unit | $0.667 | -60% |
| TIADYLT ER 240 MG CAPSULEGeneric | $0.147per tablet or unit | $0.365 | -60% |
| SAXAGLIPTIN HCL 2.5 MG TABLETGeneric | $1.18per tablet or unit | $2.89 | -59% |
NADAC is CMS's weekly survey of the invoice prices retail pharmacies pay wholesalers and makers, used by state Medicaid programs to set pharmacy payments. It is before any rebates and is not what patients pay. Each product is the median across its package codes (NDCs); over-the-counter drugs are left out. A product with no price a year ago was not surveyed then. Refreshed weekly. CMS, National Average Drug Acquisition Cost (NADAC)