Logos are each company's own site icon, matched by name through Wikidata.Company names and logos identify the companies in public FDA and registry records and do not imply endorsement.
Treats clinically typical, visible, or palpable actinic keratoses (AK) of the face or…. Sold as Aldara, Zyclara. Every FDA application for this active ingredient: 3 branded and 9 generic.
As of Nov 14, 2026, FDA lists 12 applications for Imiquimod (sold as Aldara, Zyclara), first approved Feb 27, 1997, with 5 new uses approved and 0 published complete response letters.
First approved: Feb 27, 1997
Applications: 12
New uses approved: 5
Complete response letters: 0
Medicare spending, 2025: $8.8M
First approved in the EU: Sep 18, 1998
Medicare Spending
CMS Part D and Part B, 2025, before manufacturer rebates; matched by generic name
Imiquimod
Part D
$8.8M
+20%
154,069
Zyclara
Part D
$0K
-100%
0
What Pharmacies Pay
Median price per unit across package codes in CMS's weekly NADAC survey, Nov 11, 2026, before rebates; see every drug's price change
IMIQUIMOD 3.75% CREAM: $36.36 per unitGeneric · +65% in a year
IMIQUIMOD 3.75% CREAM PUMP: $113.70 per GMGeneric · new this year
IMIQUIMOD 5% CREAM PACKET: $0.594 per unitGeneric · -18% in a year
BeselnaA drug with a new additional indication and a new dosage for the treatment of actinic keratosis (limited to the face or baldness). · Mochida Pharmaceutical Co., Ltd. · Nov 25, 2011
Clinical Trials
19 open or ongoing studies name this ingredient as an intervention, including as a comparator; newest first. See all
Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient.Drugs@FDA
Taro
Strides Pharma