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Sold as Vitrase, Amphadase, Hydase. Every FDA application for this active ingredient.
As of Nov 14, 2026, FDA lists 3 applications for Hyaluronidase (sold as Vitrase, Amphadase, Hydase), first approved May 5, 2004, with 0 new uses approved and 0 published complete response letters.
First approved: May 5, 2004
Applications: 3
New uses approved: 0
Complete response letters: 0
Medicare spending, 2025: $10K
Medicare Spending
CMS Part D and Part B, 2025, before manufacturer rebates; matched by generic name
Product
Part
Spending, 2025
Change
Beneficiaries
AMPHADASE
Part B
$10K
New
136
Clinical Trials
100 open or ongoing studies name this ingredient as an intervention, including as a comparator; newest first. See all
Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient.Drugs@FDA
