Etomidate

Sold as Amidate. Every FDA application for this active ingredient: 1 branded and 11 generic.

As of Nov 14, 2026, FDA lists 12 applications for Etomidate (sold as Amidate), first approved Sep 7, 1982, with 0 new uses approved and 0 published complete response letters.

First approved: Sep 7, 1982
Applications: 12
New uses approved: 0
Complete response letters: 0
Shortage: Current

Shortages

FDA's drug shortage list, as of Nov 13, 2026

Shortage	Status	First posted	Updated
Etomidate Injection	Current	Oct 5, 2022	Nov 9, 2026

Clinical Trials

26 open or ongoing studies name this ingredient as an intervention, including as a comparator; newest first. See all


INtubation With Sedation Only to Preserve Independent Respiratory Effort TrialAcute Respiratory Failure · Vanderbilt University Medical Center	Not applicable	Enrolling by invitation	Sep 28, 2026
Remimazolam Versus Propofol for Maintenance of Anaesthesia During Major Hepatectomy Under Low Central Venous PressureIntraoperative Hypotension, Hepatectomy · Beijing Tsinghua Chang Gung Hospital	Phase 4	Recruiting	Aug 27, 2026
Repetitive Transcranial Magnetic Stimulation for People With Etomidate Addiction (SToP-E-rTMS x Etomidate)Etomidate Use Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS) · The University of Hong Kong	Not applicable	Not yet recruiting	Jul 30, 2026
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of KL0011034 Injection in Healthy VolunteersHealthy Volunteers · Hunan Kelun Pharmaceutical Co., Ltd.	Phase 1	Recruiting	Mar 16, 2026
Comparison of Anesthetic Techniques for Early Recovery After Ankle ArthroscopyAnkle Sprain, Ankle (Ligaments); Instability (Old Injury) · Second Affiliated Hospital, Zhejiang University, School of Medicine	Not applicable	Not yet recruiting	Mar 10, 2026
Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly PatientsPostoperative Pain, Acute, Hemodynamics · Qianfoshan Hospital	Phase 4	Recruiting	Dec 9, 2025
Anesthesia Management in Endovascular Therapy for Ischemic Stroke - 2Ischemic Stroke, Anterior Cerebral Circulation · University Hospital, Clermont-Ferrand	Not applicable	Recruiting	Nov 19, 2025
The Effect-site Concentration of Remifentanil Blunting Endotracheal Intubation Responses During Anesthesia Induction With Lidocaine or Sufentanil Combined With Etomidate: A Randomized Controlled StudyHemodynamics · Peking University Shenzhen Hospital	Not applicable	Recruiting	Jul 28, 2025

Applications

NDAs, BLAs and generic ANDAs for this ingredient, oldest first; each opens its full history


Sep 7, 1982	AmidateNDA 18227 · New molecular entity	Hospira	15	Marketed
Nov 4, 1996	EtomidateANDA 74593	Hikma	2	Marketed
Jan 2, 2009	EtomidateANDA 78289	Rising	1	Discontinued
Dec 22, 2009	EtomidateANDA 78867	Luitpold	0	Discontinued
Jun 20, 2012	EtomidateANDA 91297	Ph Health	0	Discontinued
Jul 18, 2014	EtomidateANDA 202360	Zydus Pharms	1	Marketed
Aug 13, 2014	EtomidateANDA 204618	Avet Lifesciences	1	Discontinued
Feb 25, 2016	EtomidateANDA 202354	Hikma	1	Marketed
Feb 7, 2017	EtomidateANDA 201044	Mylan Labs Ltd	1	Marketed
Feb 24, 2017	EtomidateANDA 206126	Eugia Pharma	2	Marketed
Apr 18, 2017	EtomidateANDA 209058	Gland	1	Marketed
Dec 18, 2020	EtomidateANDA 215028	Caplin	0	Marketed

Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient. Drugs@FDA