Ergocalciferol

Treats hypoparathyroidism, refractory rickets, also known as vitamin D resistant rickets…. Sold as Drisdol. Every FDA application for this active ingredient: 1 branded and 13 generic.

As of Nov 15, 2026, FDA lists 14 applications for Ergocalciferol (sold as Drisdol), first approved Jan 11, 1941, with 0 new uses approved and 0 published complete response letters.

First approved: Jan 11, 1941
Applications: 14
New uses approved: 0
Complete response letters: 0

What Pharmacies Pay

Median price per unit across package codes in CMS's weekly NADAC survey, Nov 11, 2026, before rebates; see every drug's price change

ERGOCALCIFEROL 1.25 MG CAPSULE: $0.116 per unitGeneric · new this year

Clinical Trials

6 open or ongoing studies name this ingredient as an intervention, including as a comparator; newest first. See all


Efficacy of Vitamin D in Post-Stroke Cognitive ImpairmentPost-Stroke Cognitive Impairment (PSCI) · Suzhou Municipal Hospital of Anhui Province	Not applicable	Active, not recruiting	Aug 17, 2026
Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D DeficiencyCholestatic Liver Disease, Chronic Liver Disease (CLD) · Chulalongkorn University	Phase 4	Recruiting	Jun 26, 2026
Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' DiseaseGraves Disease, Graves' Disease · Northwell Health	Phase 2	Active, not recruiting	Jan 27, 2026
High-Dose vs Standard Ergocalciferol for Vitamin D Normalization in Aggressive Non-Hodgkin LymphomaVitamin D 25-Hydroxylase Deficiency, Lymphoma Non-Hodgkin · Phramongkutklao College of Medicine and Hospital	Not applicable	Not yet recruiting	Jan 26, 2026
Early Vitamin D3 Supplementation for Critically Ill PatientsVitamin D Deficiency, Critical Illness · National Taiwan University Hospital	Not applicable	Recruiting	Jul 10, 2023
Vitamin D Homeostasis in SarcoidosisSarcoidosis, Vitamin D Insufficiency · University of Texas Southwestern Medical Center	Phase 4	Recruiting	Aug 8, 2018

Applications

NDAs, BLAs and generic ANDAs for this ingredient, oldest first; each opens its full history


Jan 11, 1941	DrisdolNDA 3444	Esjay Pharma	14	Marketed
Mar 26, 1973	Vitamin DANDA 83102	West Ward	0	Discontinued
Jun 12, 1973	DeltalinANDA 80884	Lilly	2	Discontinued
Jul 13, 1973	Vitamin DANDA 80951	Impax Labs	2	Discontinued
Sep 26, 1974	Vitamin DANDA 80825	Chartwell Molecular	0	Discontinued
Oct 16, 1978	Vitamin DANDA 80704	Bionpharma	25	Marketed
May 20, 2009	ErgocalciferolANDA 40833	Chartwell Rx	0	Marketed
Dec 29, 2009	ErgocalciferolANDA 40865	Sun Pharm Inds Inc	0	Discontinued
Jul 14, 2010	ErgocalciferolANDA 91004	Sigmapharm Labs LLC	0	Discontinued
Aug 3, 2010	ErgocalciferolANDA 90455	Onesource	0	Marketed
Dec 7, 2018	ErgocalciferolANDA 204276	Puracap Pharm LLC	0	Marketed
—	Vitamin DANDA 80747	Chase Chem	0	Discontinued
—	Vitamin DANDA 80956	Everylife	0	Discontinued
—	Vitamin DANDA 84053	Vitarine	0	Discontinued

Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient. Drugs@FDA