Logos are each company's own site icon, matched by name through Wikidata.Company names and logos identify the companies in public FDA and registry records and do not imply endorsement.
Sold as Vibramycin. Every FDA application for this active ingredient.
As of Nov 15, 2026, FDA lists 1 application for Doxycycline Calcium (sold as Vibramycin), first approved Sep 23, 1974, with 1 new use approved and 0 published complete response letters.
First approved: Sep 23, 1974
Applications: 1
New uses approved: 1
Complete response letters: 0
What Pharmacies Pay
Median price per unit across package codes in CMS's weekly NADAC survey, Nov 11, 2026, before rebates; see every drug's price change
DOXYCYCLINE 25 MG/5 ML SUSP: $0.229 per MLGeneric · +4% in a year
DOXYCYCLINE 50 MG TABLET: $4.39 per unitGeneric · -28% in a year
Clinical Trials
89 open or ongoing studies name this ingredient as an intervention, including as a comparator; newest first. See all
Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient.Drugs@FDA