Diethylpropion Hydrochloride

Sold as Tepanil, Tenuate, Tenuate Dospan, Tepanil Ten-Tab. Every FDA application for this active ingredient: 6 branded and 10 generic.

As of Nov 15, 2026, FDA lists 16 applications for Diethylpropion Hydrochloride (sold as Tepanil, Tenuate, Tenuate Dospan and others), first approved Aug 6, 1959, with 0 new uses approved and 0 published complete response letters.

First approved: Aug 6, 1959
Applications: 16
New uses approved: 0
Complete response letters: 0

What Pharmacies Pay

Median price per unit across package codes in CMS's weekly NADAC survey, Nov 11, 2026, before rebates; see every drug's price change

DIETHYLPROPION 25 MG TABLET: $0.243 per unitGeneric · 0% in a year
DIETHYLPROPION ER 75 MG TABLET: $1.98 per unitGeneric · +64% in a year

Clinical Trials

3 open or ongoing studies name this ingredient as an intervention, including as a comparator; newest first. See all


Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)Cardiovascular Kidney Metabolic Syndrome · Ohio State University	—	Active, not recruiting	Sep 23, 2025
Anti-obesity Pharmacotherapy and InflammationObesity · Louisiana State University Health Sciences Center in New Orleans	—	Active, not recruiting	Mar 6, 2023
A Study to Evaluate the Safety of Exposure to Wegovy During PregnancyPregnancy, Obesity · Novo Nordisk A/S	—	Enrolling by invitation	Aug 17, 2022

Applications

NDAs, BLAs and generic ANDAs for this ingredient, oldest first; each opens its full history


Aug 6, 1959	TenuateNDA 11722 · New molecular entity	Mpp Pharma	17	Discontinued
Aug 14, 1959	TepanilNDA 11673 · New formulation or manufacturer	3m	4	Discontinued
Nov 17, 1960	Tenuate DospanNDA 12546 · New active ingredient	Ani Pharms	19	Discontinued
Mar 20, 1975	TenuateNDA 17668 · New dosage form	Sanofi Aventis US	9	Discontinued
Mar 20, 1975	TenuateNDA 17669 · New formulation or manufacturer	Sanofi Aventis US	7	Discontinued
May 25, 1977	Tepanil Ten-TabNDA 17956 · New formulation or manufacturer	3m	25	Discontinued
Aug 15, 1979	Diethylpropion HydrochlorideANDA 85741	Watson Labs	0	Discontinued
Aug 25, 1983	Diethylpropion HydrochlorideANDA 88267	Chartwell Rx	9	Discontinued
Aug 25, 1983	Diethylpropion HydrochlorideANDA 88268	Chartwell Rx	9	Discontinued
Sep 20, 1984	Diethylpropion HydrochlorideANDA 88642	Teva	0	Discontinued
Sep 16, 1994	Diethylpropion HydrochlorideANDA 85916	Sandoz	5	Discontinued
Nov 5, 2008	Diethylpropion HydrochlorideANDA 40828	Epic Pharma LLC	0	Discontinued
Dec 22, 2010	Diethylpropion HydrochlorideANDA 201212	Avanthi Inc	0	Marketed
Jul 18, 2011	Diethylpropion HydrochlorideANDA 200177	Lannett Co Inc	0	Marketed
Oct 24, 2011	Diethylpropion HydrochlorideANDA 91680	Lannett Co Inc	0	Marketed
—	Diethylpropion HydrochlorideANDA 85544	Ucb Inc	0	Discontinued

Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient. Drugs@FDA