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Treats serious infections caused by susceptible anaerobic bacteria. Sold as Cleocin Hydrochloride. Every FDA application for this active ingredient: 1 branded and 14 generic.
As of Nov 15, 2026, FDA lists 15 applications for Clindamycin Hydrochloride (sold as Cleocin Hydrochloride), first approved Feb 22, 1970, with 3 new uses approved and 0 published complete response letters.
First approved: Feb 22, 1970
Applications: 15
New uses approved: 3
Complete response letters: 0
Medicare spending, 2025: $15.0M
Medicare Spending
CMS Part D and Part B, 2025, before manufacturer rebates; matched by generic name
Clindamycin HCl
Part D
$15.0M
-11%
1,490,396
Cleocin HCl
Part D
$0K
+42%
42
What Pharmacies Pay
Median price per unit across package codes in CMS's weekly NADAC survey, Nov 11, 2026, before rebates; see every drug's price change
CLINDAMYCIN (PEDI) 75 MG/5 ML: $0.133 per MLGeneric · -19% in a year
CLINDAMYCIN 2% VAGINAL CREAM: $1.87 per GMGeneric · +19% in a year
CLINDAMYCIN HCL 150 MG CAPSULE: $0.105 per unitGeneric · -2% in a year
CLINDAMYCIN HCL 300 MG CAPSULE: $0.179 per unitGeneric · -2% in a year
CLINDAMYCIN HCL 75 MG CAPSULE: $0.269 per unitGeneric · -11% in a year
CLINDAMYCIN PHOSPHATE 1% FOAM: $1.97 per GMGeneric · -36% in a year
CLINDAMYCIN PHOSPHATE 1% GEL: $3.63 per MLGeneric · -55% in a year
CLEOCIN 100 MG VAGINAL OVULE: $60.24 per unitBrand · +3% in a year
CLEOCIN 2% VAGINAL CREAM: $1.79 per GMBrand · +2% in a year
Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient.Drugs@FDA