Logos are each company's own site icon, matched by name through Wikidata.Company names and logos identify the companies in public FDA and registry records and do not imply endorsement.
Treats newly-diagnosed low-risk acute promyelocytic leukemia (APL). Sold as Trisenox. Every FDA application for this active ingredient: 1 branded and 12 generic.
As of Nov 15, 2026, FDA lists 13 applications for Arsenic Trioxide (sold as Trisenox), first approved Sep 25, 2000, with 1 new use approved and 0 published complete response letters.
First approved: Sep 25, 2000
Applications: 13
New uses approved: 1
Complete response letters: 0
Medicare spending, 2025: $575K
First approved in the EU: Mar 5, 2002
Medicare Spending
CMS Part D and Part B, 2025, before manufacturer rebates; matched by generic name
Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient.Drugs@FDA
Fresenius Kabi USA
Zydus Pharms
Eugia Pharma
Sandoz