Treats superficial infections of the external auditory canal caused by organisms…. Sold as Vosol, Acetic Acid 0.25% In Plastic Container. Every FDA application for this active ingredient: 4 branded and 7 generic.
As of Nov 15, 2026, FDA lists 11 applications for Acetic Acid, Glacial (sold as Vosol, Acetic Acid 0.25% In Plastic Container), first approved May 17, 1960, with 0 new uses approved and 0 published complete response letters.
| Vinegar and HeartburnHeartburn · Arizona State University | Not applicable | Recruiting | Nov 10, 2026 |
| C2001P-CS6: Testing the Feasibility of Different HPV Screening and Care Strategies for Women Living With HIVHuman Papillomavirus (HPV), HPV Associated Cancers · University of California, San Diego | Not applicable | Recruiting | Nov 9, 2026 |
| Acetic Acid Ear Drops Versus 0.3 % Ciprofloxacin for Chronic Suppurative Otitis Media.Otitis Media Chronic · Dow University of Health Sciences | Not applicable | Not yet recruiting | Sep 22, 2026 |
| Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized PatientsAlcohol Withdrawal, Alcohol Abstinence · University of Colorado, Denver | Phase 1 / Phase 2 | Not yet recruiting | Sep 9, 2026 |
| VIA Versus ColposcopyCervical Intraepithelial Neoplasia (CIN), Cervicitis · Sohag University | — | Not yet recruiting | Jul 9, 2026 |
| NIMBLE-CRC: NeoImmunoModulation Before Leveraging Excision in Colorectal Rectal CancerColon Cancer Metastatic · Northwell Health | Phase 2 | Not yet recruiting | Jul 1, 2026 |
| Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in Women Living With HIVCervix Cancer, HIV Infections · UNC Lineberger Comprehensive Cancer Center | Not applicable | Not yet recruiting | Jun 3, 2026 |
| Impact of Acetic Acid-Indigo Carmine Chromocolonoscopy on Proximal Sessile Serrated LesionsSessile Serrated Lesion · Changhai Hospital | Not applicable | Not yet recruiting | May 22, 2026 |
| May 17, 1960 | VosolNDA 12179 · New combination | Hikma | 11 | Discontinued |
| Jun 2, 1976 | Acetic Acid 0.25% In Plastic ContainerNDA 17656 · New formulation or manufacturer | Otsuka Icu Medcl | 36 | Marketed |
| May 11, 1977 | Acetic AcidANDA 85493 | Kv Pharm | 0 | Discontinued |
| Aug 6, 1979 | Acetic Acid 0.25% In Plastic ContainerNDA 18161 · New formulation or manufacturer | B Braun | 20 | Marketed |
| Oct 26, 1979 | OrlexANDA 86845 | Warner Chilcott | 0 | Discontinued |
| Aug 12, 1981 | AcetasolANDA 87146 | Actavis Mid Atlantic | 11 | Discontinued |
| Feb 19, 1982 | Acetic Acid 0.25% In Plastic ContainerNDA 18523 · New formulation or manufacturer | Baxter Hlthcare | 13 | Marketed |
| Sep 6, 1984 | Acetic AcidANDA 88638 | Sun Pharma Canada | 14 | Discontinued |
| Jul 26, 1996 | Acetic AcidANDA 40166 | Chartwell Rx | 1 | Discontinued |
| Feb 24, 2005 | Acetic AcidANDA 40607 | Sciegen Pharms | 1 | Marketed |
| Mar 9, 2018 | Acetic AcidANDA 207280 | Rising | 0 | Marketed |
Applications, approvals and products come from FDA's Drugs@FDA data files, refreshed weekly, grouped by active ingredient as FDA spells it. Complete response letters are FDA's published letters. Medicare spending is CMS's Part D and Part B dashboard, matched to this ingredient by generic name; shortages are FDA's shortage list, matched by application number; clinical trials are ClinicalTrials.gov studies naming the ingredient as an intervention, refreshed daily; safety programs are FDA's REMS list, matched by application number or, for shared programs, by ingredient. Drugs@FDA
Hikma
Baxter Hlthcare
Sun Pharma Canada