Penthrane

NDA 13056, held by Abbott. Methoxyflurane.

As of Nov 13, 2026, NDA 13056 (Penthrane), held by Abbott, was first approved by FDA on May 4, 1962, with 6 approved supplements and 0 published complete response letters.

First approved: May 4, 1962
Review: Priority
Supplements approved: 6
Complete response letters: 0

Approvals and New Uses

The original application and every efficacy supplement, newest first; all 7 submissions below

Date	Submission	Status	Documents
May 4, 1962	Original applicationNew molecular entity · Priority review	Approved	None posted

Products

1 strengths and forms

Product	Active ingredient	Marketing
Penthrane99.9% · liquid; inhalation	Methoxyflurane	Discontinued

All 7 submissions, including labeling and manufacturing supplements


Sep 17, 2001	Supplement 28Labeling · Standard review	Approved	None posted
Sep 17, 2001	Supplement 20Labeling	Approved	None posted
Feb 1, 1984	Supplement 24Labeling	Approved	None posted
May 25, 1978	Supplement 21Labeling	Approved	None posted
Aug 28, 1974	Supplement 18Labeling	Approved	None posted
Oct 2, 1972	Supplement 14Labeling	Approved	None posted
May 4, 1962	Original applicationNew molecular entity · Priority review	Approved	None posted

Identifiers

Application: NDA 13056
Drugs@FDA: Overview at FDA
Company: Abbott

Approvals, supplements, products and documents come from FDA's Drugs@FDA data files, refreshed daily; Drugs@FDA lists approved applications only. Complete response letters are FDA's published letters. Drugs@FDA and FDA complete response letters